Thermo Scientific Chemicals for Analytical Applications

Complete Your Analyses with Confidence

As a leader in analytical chemistry, the Thermo Scientific™ brand offers a comprehensive collection of high-purity and high-quality chemicals specifically designed to support various projects, methods, and assays while meeting the requirements of your laboratory.

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Within our collection, you’ll find the right grade and chemical specification for your application, as well as products suitable for a range of analytical techniques, including sample preparation and extraction, chromatography, mass spectrometry, and trace elemental analyses.

Accuracy and reliability are important in analytical chemistry, which is why Thermo Scientific chemicals are carefully formulated. Whether you’re performing routine analyses or advanced research, you’ll be able to find a dedicated range of solvents and reagents in various purities that will meet your preparative and analytical needs.

Learn more about:

• Chromatography consumables
• Chromatography and mass spectrometry chemicals
• Ion chromatography standards
• Trace elemental analysis acids and standards

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Browse Chemicals and Consumables for PFAS Testing

LC-MS-Grade Solvents, Reagents, and Mobile Phase Solutions

As new regulatory limits and instrumentation developments lead to ever-lower analyte detection limits, there is an increased need to reduce noise, which can impact the overall performance of LC-MS applications and methods.

That’s why these LC-MS products are manufactured using additional purification processes, quality control measures, and packaging innovations—to help reduce or eliminate the presence of phthalates, PEG, and other contaminants. This helps provide low mass noise levels and minimize organic contamination and metal content to meet the high-purity demands of LC-MS applications. 

Thermo Scientific LC-MS Grade Products

• See more analytes: With very low background observed in comparison to other lower grade solvents, you’ll be able to get a better signal/noise ratio from your analytical peaks, helping you better detect your analytes even at trace levels.
• Reduce adduct formation: Up to 17 metals are specification tested and reported in our certificate of analysis.
• Help your system run more efficiently: Filtered at 0.1 μm, these products help reduce instrument, column, and check valve clogs.
• Save time and money: Consider pre-made mobile phases, such as acetonitrile + 0.1% formic acid, so you can focus on other priorities in the lab.

UHPLC-MS-Grade Solvents and Kits

When ultimate sensitivity and purity is essential, find the products you need to deliver highly accurate results at the lowest levels of detection. Browse chemicals that are suitable for all applications and markets and are recommended for use with all chromatography systems, especially those that run columns with smaller particle sizes (less than 3 µm), such as UHPLC, micro, and nano-LC systems, and use mass spectrometry as the detection technique.

UHPLC-MS-Grade Products

• Reduce adduct formation: These products are packaged in borosilicate bottles to help ensure extremely low leachable sodium and potassium levels and reduce adduct formation. Tight metal specifications also minimize metal ion adduct formation.
• Help your system run more efficiently: Filtered at 0.1 μm, these products help reduce instrument, column, and check valve clogs.
• Eliminate leachables: No fluoropolymer liners are used in the caps, helping to eliminate background interference during PFAS analyses.

Heavier workloads = less time per sample

A growing list of aqueous contaminants and increasingly stringent regulatory requirements require labs to process more samples in less time, without sacrificing accuracy.

The nature of the samples measured in environmental laboratories is such that sample preparation is required—this always involves filtering the samples, and in many cases diluting them as well. This procedure is the only way to prevent damage to the analysis system and to achieve accurate results.

Want more information on Ion Chromatography & Sample Preparation Solutions? Feel free to contact us.

However, sample preparation is an expensive step, as it involves a significant amount work as well as costly consumables.

(Ultra)filtration

All aqueous environmental samples must be filtered prior to analysis. This prevents particles from the sample contaminating or blocking the separation column, significantly extending its lifetime. The high volume of samples at the lab involved in this study drove material cost down to only $1 USD per syringe filter. However, since each individual sample requires a new filter, with 14,300 samples a year this still amounts to $14,300 – just for filtration materials!

The integrated ultrafiltration in the ion chromatography system from Metrohm only needs one filter change per day, saving this laboratory over $12,000 per year. What’s more, the ultrafiltration process is fully automated.

Compared to manual filtration, this saves three minutes of working time per sample. With labor costs of $18 per hour, this again corresponds to savings of around $13,000 per year.

Suppression

Suppression reduces the conductivity of the eluent, resulting in a more sensitive conductivity detection of the analyte. This makes it possible to achieve particularly low limits of detection and quantification.

The instrument previously used at this laboratory (from a different supplier) employed membrane-based suppressors. These suppressors have to be replaced every three months, costing approximately $1,200 each time. The Metrohm Suppressor Module (MSM), on the other hand, is a one-off purchase because it utilizes ion exchanger particles in a robust micro-packed bed for suppression instead of membranes. The three suppression cartridges of the MSM alternate between suppression, rinsing, and regeneration, thereby ensuring continuous suppression at all times.

The regeneration reagents are inexpensive, averaging $52 per 1,000 samples, resulting in total annual costs of $750 for 14,300 samples. This is much cheaper than the cost of replacing a membrane suppressor multiple times!

Automatic Inline Dilution eliminates this expense: the analysis system dilutes the relevant samples fully automatically and then measures them again. This makes the laboratory much more efficient: the daily sample throughput increases, and samples with a limited shelf life are always analyzed in good time.

Find out more about the many different Metrohm Inline Sample Preparation options available here:

Metrohm Inline Sample Preparation

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